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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7bb8a9bf408084d30be5b1c576828e055db5c0e0e2f4f1519ffbd8427fd141' 
  AND token = 'MOue2ghWoFnPy8eo9xgTUkRd9r1cB+qXmSBZSQO4sC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}