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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff384fab44b3cfdef3383514b164d5c95a60d18b13da36efb141ac785cd150f' 
  AND token = 'PQxzz1avHiBOe0liW1jVnQPhVh616knEYk0tWNy5t64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}