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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343f4990df08d4556d7fe754d3424c3b7fde36890456fd4cfce87739817f2572' 
  AND token = 'AjAj/rbGc6QqrTji3+pSI3oOojQ8u6e2oaKM3tQ4nhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}