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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '415b0e2454a46c042c349f6f97f165f7d0ddce759ab343e35717c57cc8fdfe22' 
  AND token = 'sRd29VcXsgFtxi6+KToIICgFQy8m++ej4ZZ9Vy/L0d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}