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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f9401d6413530472cd0f57545e807576f1ffd0063b429c97877e013d12a600' 
  AND token = 'ODJ9X03nZM7LaOCyth7Ye+BKzCPvNpDxgY25TffMpqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}