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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c2d7cc9dbab26c1c2b82a09159f95746c6e8f5e52350afbb5b4765f01d2e4f' 
  AND token = '6Vr72PJoFWOPtSXqlJPrKVtc7FcueULxtkG8E+rn8w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}