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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2a81a2fd8b0135b0ab369fa4422b895637b8645fa857c1cb5d4304460b4e58' 
  AND token = 'ejssdDMTdSoUOlvuHn7Q5VtdWD/oaxAaq0WXhYV90bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}