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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ce78b256f1be7ecfcbf43c435ce44338acc2d0a87ab3cce21c77e51be68fd8' 
  AND token = 'H/VipdqABbAXYXn5w+EVrGn5m/GbS6YlJuU1GadjTEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}