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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746c7f4fcc7da8dcf7db2f000528c2430fe55c3c8b4dc165b339ea43516eb392' 
  AND token = 'GT3aTMFnnyTXZffa1lHrQZFEqrgWGZWzSJ2bo8o1b5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}