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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadb302971f9124eef8cba79a63f9098ea2e1be1a2f88dd5fd8955bd659c89b4' 
  AND token = 'd14Tf8fzXnSxHWLZhwG2IYNRMnTPAg1xl8ukHtQzXr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}