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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2914a2a1fb9cc41aec59333dacfc94e5294195b6e87d83571da3e61b29a001d3' 
  AND token = 'mTYg/OG/29MydrUzm73ic6AzKtcgAEDD3ov2Xsr3vxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}