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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff21720a09b63113d2c0caded92777c19bb4babc9fbb80aba8481b5b999fc94e' 
  AND token = '8ySxBTZ5vnIWvTftPizNUeN7AZMbjg9r2HXMaiBfwSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}