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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5fa7e1ab63998317a9ab28ffca3034dfd24f4ebbde3b2c4a2095fe0d6cd6e2c' 
  AND token = 'AfiqtsJ9j0U+OSNMI3sXbnnBw8z4HdTZRLBMsv4XT1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}