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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee07e0f2aa34e332af6857426e1882ff62bd255e4af335828ab50e37c48fbd56' 
  AND token = 'E9AuHwUdnf4KZkCxxFpzXG4eXtCOGYJ4Mt1t+ROdfEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}