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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a725da2ceb4cf406f839a956217102175aba28de6cd849eeb5e0843649e301' 
  AND token = 'ps3LNZ1w3is6gaD4TD2dBcbvHkMV3t9duWr6yoMg6w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}