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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cec2c4cda34ef77e382d94e363f5eb2562af619b31b1e736b413cd6c750718de' 
  AND token = 'o2vpSqZR7hnrPOfW2KueXSQh6jse+D3jdjrwgluVQIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}