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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82a82bfaaf50bede0d71d3e60f031df71e10ad091d8ee8cc63f3778fcd8a1ed9' 
  AND token = 'UodLVHdX5Dmhy8jTVy+SmFYQcKeVGtuwZMspS7uw5tA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}