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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bedb9bb8225071ab734ab5b96a7e800318f1d0f4af37bea6a20ac50dbbb5a56' 
  AND token = 'oXIS3KjAPGsOsqFQzB6V237sgrJDgU+oUJ2L1USkyjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}