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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af854eaedc94448c8fe50dd3125215c48a4cf8b8f72a8851ce7eb7e5f42b1b21' 
  AND token = 'tng1qUpm+Mo+dPJnsTk1g3KRTorPCKXoxA6tb3sPqi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}