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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10441f6f269b7ff8d8f2db1281337478f488be14af73fb503978a68fff733a83' 
  AND token = 'E8uYQgbjh5ktfsN0JwflIUp2VTMf8X2T781ZMtVcDcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}