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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4b8ff571356958d72d49ae1de6ea80418154eb6698f5534a7d9aa288135d1c' 
  AND token = 'eMC73FV3p/Z0VZHX0090BewlR7bCf+uM1Wk7YKNmF+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}