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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac6ddfb958a094006ac52e2a573e180a9ed64a225fb09068a608c2565845a6b3' 
  AND token = 'Rz0ylIJ+VYnxS0pA/0NxaCzC6I0VqXxHZgj+inQk5Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}