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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeba76b064f0cea06567e33e0ea3d0fc666bbb4b45bd737443abcce7ed574815' 
  AND token = 'JD2IoRV5hU+pPYGHay2T+dJg1g96VJ8pr9ignR9uwfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}