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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3952505074aed77b74996a080d18cfecdbe219de69c38b0b32bfdc7a0d1673c' 
  AND token = 'G43isO+mXGGEaNwSu86Uj24cOn/3d+jjhkzyE3iFK08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}