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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45adeb1bf831136ec54a72592c0d33a737f0c92313be0f7b5b807a7eca7df35' 
  AND token = '54FdoJX49nebEKqg2yxpR7DZouXg7jdJqL6fj1+7RrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}