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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64892cffc04be0ae4a35b1164d473aa8661c5d54a8637710f53318c0a9e82506' 
  AND token = 'ofEtWjh0r3G51WOdMUf+fgelvSaqM+NHdnQ9EwIfJIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}