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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b974a09d8d0db5bb2a4413bff759fcc6780b32b6dfd8c13b363a269d884dc122' 
  AND token = 'h7o6Vv1z/pri9SmsDkAv0NRcTJ8UrHjUz9t2VBPU7a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}