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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f888d423c4c18b616092c38db6c39ed97173222f4ea0d839255aa5c33b0aef43' 
  AND token = 'ZqLYcK29v2C2XUrOEZ5PrCrnw9hlB+D1Uli1bFY2gdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}