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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2113095e1f282a706fb024aa63051ab1f2968e1384b29eda3c2b8e2bdb2e7dcf' 
  AND token = '65QH5WEf8XAHBA274msxQF26F0ihLwaspvDnxulKZ80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}