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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80b63e89f90eb6461a9b3f72b347ddc98a85763ff50a0145b5994a78d049701' 
  AND token = 'o5MJUJ27rQrY8MD1HKIZ4WSzjoR57MsJnepMBHE4UQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}