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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0687cc3c31280da7e8b843b152d5945ac7c049bbba1c0a42c5f459a175db8d59' 
  AND token = 'zeCgniasaZQK7P0pg9Np7CfVROmv6BmjR2rfyuLELzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}