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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53b5bf3dac12f95d8dc70259a2aba511fdf1da059705ce3f50e3e312ffdeae4' 
  AND token = 'LoNWN0rLe9IaRE6M3Pz7HnDjpEfG/husLbOGYytL1k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}