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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9000e80ff270c0153426dd3994a83e0b5d191cbaa68be3bdee116b8a5301d5f2' 
  AND token = 'rIES+WN8hL2C7G48jP4QUZNqd0ng1m/+LHdZdZFSw/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}