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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f59194d2c74efd95cb82d5e251cb278b987fc86d87f64f026c5fd3f5e8da50' 
  AND token = 'cnyN3b1UgdhNTWH43KNO8osJm/T5Jsnk20MgW04gNq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}