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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc77842b50b1dc7f3a93cd7da3544a7aa8bfeacedc36cb26958cf4127dc4d91' 
  AND token = 'dx/pXSBxOSNDcroOIS2BviR+9H5c0EQCyLr2S5YYzvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}