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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6655cd5badb2fa7b67e185445563c2eb5df18b0fc3b4f213db97bbb4e8d565' 
  AND token = 'T5N7Uae7nYK4UocD+Vw63HjgU/NS56iPi1qcEYJV6Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}