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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b2a3d953df13a124f474f746b61b815f66c097268f6ae819b23d45eaf0fe8a6' 
  AND token = 'K4N1An5b2Db9/MtTS6Ntvq4OO8f2DiWCMmJdwO8JLtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}