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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd756d3e191addedf12d794476dd769bdbb1e6878e9727352a785b9aaf426f0e9' 
  AND token = 'Nr2qM3nDxBxEVXnYKk17Xcmvl2aclVDXj1jImwR2Gpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}