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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a55ae9f04e4352a1654c1d19d93937751e8b3a698e6877d92e8263241a49e7' 
  AND token = 'h4I+B98qw+qRLU8r7xea2RKQ42wCBfTrKH3rqO7wOzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}