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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd7b63345c82aedb5ecbcb8b162c6eafc8294f5861f2f7eb9c8ca18b485af83' 
  AND token = 'eHlb5kDVn/G4W78V5bxUOpIWrjux6CQG/FeViQucUKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}