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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878044343a53f0eaf23c0ea13dc810ab90c3ea17f501d9937a3b7d2670015c9a' 
  AND token = 'EN53PIbeBPK5Bc76qmfCaidDdKrRBGgU/hgQ4tIFGls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}