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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f0bf255dfb24199fd4d78287e2ae091e6f2301161315509582095a8103631c' 
  AND token = 'p6Ja+rzSBmmBa8MlILBWaVoE8fG5kuj3Bm2PN6fmU1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}