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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8472f20784fa3be457e093fc9bf53c75b19ada2d56d06d3f6eeff1a8735eb069' 
  AND token = 'iirg/bJJcisfJZfJlxKm5neft3Z/8xfo6k99PqVC/mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}