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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2e49b84d86428c4fae89a703e6a9d7853ed7a459e2338f05214d05b6df9a83' 
  AND token = 'n0IwtVLqQeC6ktRbKdaTljmqIKXgmHImFLbM6+Vbv6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}