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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c5a944ebf1d5b4088390e7d35a72b6970c39e43476d44daeece8728a5d0c99' 
  AND token = 'l/HHTtEVkZOa6aMZPionjZg3lB9hdL9CheBcLX/M6Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}