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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e781536bd15d23a7ca3f33d9ff31a917ff5c88526c5d22dff5fbcaefbfac3b3c' 
  AND token = '6ah9cxT1MuF9jG8xHvSlC9nR+edFgDgkBZgKwS2udWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}