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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3254ed5768d60b5cdfa144a9f361bc889f846e5e854e6fb7f594801a8d5bf521' 
  AND token = 'wYyExC0wANjWadgqfbqW+NiJ2QfbLq185xry7wKcJbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}