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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6a7ed22c95a6d4ef67b6c65cbb85f5a4d0d8a7764bb3b448b0dec23986f7cb' 
  AND token = 'VQNI1Z02fcifj12SnmS1rcowHphK2xxKHbfUX3Wit1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}