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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2d874dd1090132504ccb667038cd426fa7af23e5edb3ec39c1f95e1dca570a' 
  AND token = 'QAQdOn6mcIl1U+mtZN74CyTgoOPd5vxVkDELFy0a3jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}