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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ede4cd64a49ec94c3142d4a82bbeb43a1c5abd408c790f79a243fce4cea2f57' 
  AND token = 'FvnwMXNX/4kevH4uZ0LyGzJeKQ36flYB0cbRaKYt5qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}